Over the recent decades, unrelenting efforts are being devoted to the sustainable design and synthesis of transitional metal oxide-based photocatalysts with controlled morphology and structural complexity to enhance their catalytic properties. In this account, we have reported the bio-fuel-assisted hydrothermal synthesis of MoO₃, MoO₃:NiO, and MoO₃:PdO/Pd as catalysts to remove azo pollutants from an aqueous solution. Methyl orange was selected as the model dye to represent organic pollutants. This work presents a facile method for improving the visible-light-driven catalytic activity of MoO₃ by introducing NiO and PdO. When MoO₃:NiO and MoO₃:PdO/Pd were illuminated by solar light, emitted radiation originating from oxygen vacancies of NiO and PdO synergistically participated in catalytic reactions of MoO₃ giving 98% and 95 % degradation of methyl orange, respectively, in 15 min. To confirm the supporting role of NiO and PdO in the catalysis of MoO₃, catalytic experiments were carried out in dark ambient conditions, with only catalysts (without stimulants). Subsequently, the degradation efficiency of MoO₃:PdO, and MoO₃:NiO was increased to 73% and 84% respectively, from 62 % efficiency of MoO₃ suggesting that NiO and PdO greatly increased the efficiency of MoO₃ in dark conditions and nearly complete removal of methyl orange by photo-induced visible light degradation. Furthermore, the photocatalysts illustrated good reusability till four runs of experiments without loss in its degradation efficiency. Therefore, the overall catalytic results of the current study are highly proposing MoO₃:PdO and MoO₃:NiO as excellent photocatalysts for water remediation.